Enzymatic cleavage of m7 GDP from eucaryotic mRNA
نویسندگان
چکیده
منابع مشابه
Enzymatic cleavage of S-adenosylmethionine.
S-adenosylmethionine, known for some time to be the biological methyl donor in mammalian enzymatic transmethylation reactions (1,2), has more recently been implicated in other transalkylation reactions in bacteria and yeast (3-6). The enzyme system catalyzing the condensation of ATP and methionine to form AMe’ has been found in a variety of tissues and organisms, and has been purified from two ...
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The transfer of genetic information from nucleic acid to protein inside cells can be re, presented as shown in Fig. 1. This simple scheme reflects accurately the fact that the information contained in the linear arrangement of the nucleotides in DNA is copied accurately into the linear arrangement of nucleotides in RNA which, in turn, is translated by machinery inside the cell into proteins, th...
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The hybridization of a DNA oligonucleotide a specific tetramer or longer) will direct a cleavage by RNase H (EC 3.1.4.34) to a specific site in RNA. The resulting fragments can then be labeled at their 5' or 3' ends, purified, and sequenced directly. This procedure is demonstrated with two RNA molecules of known sequence: 5.8S rRNA from yeast (158 nucleotides) and satellite tobacco necrosis vir...
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Ring cleavage occurred when 1,2,4-triazino-1,2,4-triazines (3), (4) and (5) were treated with concentrated hydrochloric acid to yield N-substituted triazines (7) and (8). These confirm the given configuration assigned to the isomeric triazinotriazines. 6-Methyl-2-phenyl-7H-oxazolo [3,2-b][1,2,4]-triazin-7-one (9) underwent ring cleavage on treatment with sodium alkoxide to afford 3-alkoxy-1...
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MicroRNAs (miRNAs) are endogenous approximately 22-nucleotide RNAs, some of which are known to play important regulatory roles in animals by targeting the messages of protein-coding genes for translational repression. We find that miR-196, a miRNA encoded at three paralogous locations in the A, B, and C mammalian HOX clusters, has extensive, evolutionarily conserved complementarity to messages ...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1976
ISSN: 0014-5793
DOI: 10.1016/0014-5793(76)80896-4